- binding kinetics
- кинетика связывания
Англо-русский медицинский словарь. 2012.
Англо-русский медицинский словарь. 2012.
Binding potential — In pharmacokinetics and receptor ligand kinetics the binding potential (BP) is a combined measure of the density of available neuroreceptors and the affinity of a drug to that neuroreceptor. Description Consider a ligand receptor binding system.… … Wikipedia
Enzyme kinetics — is the study of the chemical reactions that are catalysed by enzymes, with a focus on their reaction rates. The study of an enzyme s kinetics reveals the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled,… … Wikipedia
Michaelis–Menten kinetics — An example curve with parameters Vmax=3.4 and Km=0.4. In biochemistry, Michaelis–Menten kinetics is one of the simplest and best known models of enzyme kinetics. It is named after German biochemist Leonor Michaelis and Canadian physician Maud… … Wikipedia
Receptor-ligand kinetics — In biochemistry, receptor ligand kinetics is a branch of chemical kinetics in which the kinetic species are defined by different non covalent bindings and/or conformations of the molecules involved, which are denoted as receptor(s) and ligand(s) … Wikipedia
Cooperative binding — In biochemistry, a macromolecule exhibits cooperative binding if its affinity for its ligand changes with the amount of ligand already bound. Cooperative binding is a special case of allostery. Cooperative binding requires that the macromolecule… … Wikipedia
Microscale thermophoresis — (MST) is a technology for the analysis of biomolecules. Microscale Thermophoresis is the directed movement of particles in a microscopic temperature gradient. Any change of the hydration shell of biomolecules due to changes in their… … Wikipedia
Methods to investigate protein–protein interactions — There are many methods to investigate protein–protein interactions. Each of the approaches has its own strengths and weaknesses, especially with regard to the sensitivity and specificity of the method. A high sensitivity means that many of the… … Wikipedia
Immunoprecipitation — (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein. This process can be used to isolate and concentrate a particular protein from a sample containing many… … Wikipedia
Schild regression — analysis, named for Heinz Otto Schild, is a useful tool for studying the effects of agonists and antagonists on the cellular response caused by the receptor or on ligand receptor binding. Using a dose response curve or an equivalent curve with… … Wikipedia
Development of dipeptidyl peptidase-4 inhibitors — Dipeptidyl peptidase 4 inhibitors (DPP 4 inhibitors) are enzyme inhibitors that inhibit the enzyme dipeptidyl peptidase 4 (DPP 4) and are a potent treatment for type 2 diabetes. Inhibition of the DPP 4 enzyme prolongs and enhances the activity of … Wikipedia
Self-assembled monolayer — Self assembled monolayers (SAMs) are surfaces consisting of a single layer of molecules on a substrate. Rather than having to use a technique such as chemical vapor deposition or molecular beam epitaxy to add molecules to a surface (often with… … Wikipedia